Is it possible to cancel my student registration request if I cannot join the study programme?

Yes it is possible, however there are deadlines for doing so if you wish to avoid paying tuition fees.

You can request termination of your registration, via Studielink, until the day preceding your programme's official start date - at the latest. For example, if your programme starts on 1st September, you can cancel your registration until 31st August without paying tuition fees. If you cancel your registration after this date, you will become liable for tuition fees for the period during which you were registered.

Be aware that earlier cancellation deadlines apply for visa and housing requests.